Lucknow Speciality Pharma

Trabectedin Injection 1 mg
Trabectedin injection is used to treat liposarcoma (a cancer that begins in fat cells) or leiomyosarcoma (a cancer that begins in smooth muscle tissue) that has spread to other parts of the body and cannot be treated with surgery in people who have already been treated with certain chemotherapy medications. To get access, please contact Patient Support Team @ +91 9760014849 / 9555306364 / 9794360370 / 9140551027, Time 9 am - 8 pm IST or send us a request on email (urgent@lucknowpharma.com) / WhatsApp for the same.
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Trabectedin Injection was approved for medical use in the United States in 2015. It is on the World Health Organization’s List of Essential Medicines.

Trabectedin Injection Available Price In Lucknow Banaras Nepal

Trabectedin Injection

  • Generic Brand Available – Trabec
  • API – Trabectedin
  • Packaging – Glass bottle
  • Strength – 1 mg

What is Trabectedin Injection used for?

Trabectedin injection is used to treat liposarcoma (a cancer that begins in fat cells) or leiomyosarcoma (a cancer that begins in smooth muscle tissue) that has spread to other parts of the body and cannot be treated with surgery in people who have already been treated with certain chemotherapy medications

    Facts of Medicines

    Trabectedin Injection 1 mg

    STORAGE AND HANDLING

    Trabectedin Injection must be refrigerated at 2°C to 8°C (36°F to 46°F). Do not use the Trabectedin Injection injection beyond the expiration date located on the carton and the vial.

    DOSAGE

    Administer at 1.5 mg/m2 body surface area as a 24-hour intravenous infusion, every 3 weeks through a central venous line

    Premedication: dexamethasone 20 mg IV, 30 min before each infusion For injection: 1 mg sterile lyophilized powder in a single-dose vial

    SIDE EFFECTS

    The most common (≥20%) adverse reactions are nausea, fatigue, vomiting, constipation, decreased appetite, diarrhea, peripheral edema, dyspnea, headache. The most common (5%) grades 3-4 laboratory abnormalities are: neutropenia, increased ALT, thrombocytopenia, anemia, increased AST, and increased creatine phosphokinase.

    WARNINGS AND PRECAUTIONS

    Neutropenic sepsis: Severe, and fatal, neutropenic sepsis may occur. Monitor neutrophil count during treatment. Withhold YONDELIS for Grade 2 or greater neutropenia

        FAQs – Medicine Questions

        Trabectedin Injection 1 mg
        Is trabectedin approved by FDA?
        On October 23, the Food and Drug Administration (FDA) approved trabectedin (Yondelis®) for the treatment of two subtypes of soft tissue sarcomas: liposarcoma and leiomyosarcoma.
        How does Yondelis work?
        How it works. Trabectedin works by sticking to the DNA in cells and damaging it. This stops the cancer cells growing and multiplying.
        How is trabectedin made?
        Trabectedin is natural product derived from the Caribbean sea squirt which has antineoplastic activity and is used to treat soft tissue sarcoma.
        Where can I buy Trabectedin Injection?

        You can buyTrabectedin Injection from any authorized whole-seller after getting a prescription from a qualified doctor. It is always better to check the credential of the whole-seller/supplier/exporter before buying the product.

        The buyer should check the existing law in their home country before importing the product.

        What is the procedure to buy Trabectedin Injection?

        Patients can simply fill the order form or can send mail at info@lucknowpharma.com. Patients can also send WhatsApp messages to +91-9555306364 We will reply ASAP with the details of the Trabectedin Injection price as well as procurement procedure.

        Note:- The order will be confirmed only after the receipt of the Valid prescription of the Clinician.

        How is Yondelis administered?
        YONDELIS ® is administered as an intravenous infusion over 24 hours through a central venous line every 21 days (3 weeks), until disease progression or unacceptable toxicity. YONDELIS ® may be administered to inpatients or outpatients, via stationary or ambulatory pump, at the physician’s discretion.

        NEWS / UPDATES

        1. Janssen Pharmaceutical Companies, [Revised on Jun 2020] [Accessed on 2nd Jun 2021], https://www.janssenlabels.com/package-insert/product-monograph/prescribing-information/YONDELIS-pi.pdf
        2. Pharma Mar, Electronic Medicines Compendium (EMC), [Revised on Jul 2020] [Accessed on 2nd Jun 2021], https://www.medicines.org.uk/emc/files/pil.6164.pdf
        3. Uboldi et al., Mechanism of action of trabectedin in desmoplastic small round cell tumor cells, BMC Cancer, 2017, [Accessed on 2nd Jun 2021], https://bmccancer.biomedcentral.com/track/pdf/10.1186/s12885-017-3091-1.pdf
        4. Demetri et al., Efficacy and Safety of Trabectedin or Dacarbazine for Metastatic Liposarcoma or Leiomyosarcoma After Failure of Conventional Chemotherapy: Results of a Phase III Randomized Multicenter Clinical Trial, Journal of Clinical Oncology, 2016, 34(8), [Accessed on 2nd Jun 2021], https://ascopubs.org/doi/pdfdirect/10.1200/jco.2015.62.4734