WARNINGS AND PRECAUTIONS

• Before taking tucatinib, tell your doctor or pharmacist if you are allergic to it; or if you have any other allergies. This product may contain inactive ingredients, which can cause allergic reactions or other problems. Talk to your pharmacist for more details.

• Before using this medication, tell your doctor or pharmacist your medical history, especially of: kidney disease, liver problems.

•  Before having surgery, tell your doctor or dentist about all the products you use (including prescription drugs, nonprescription drugs, and herbal products).

•  Since this drug can be absorbed through the skin and lungs and may harm an unborn baby, women who are pregnant or who may become pregnant should not handle this medication or breathe the dust from the tablets.

•  Tell your doctor if you are pregnant or plan to become pregnant. Women of childbearing age should have a pregnancy test before starting treatment. You should not become pregnant while using tucatinib. Tucatinib may harm an unborn baby. Men with female partners of childbearing age should ask about reliable forms of birth control while using this medication and for at least 1 week after the last dose.

• Women of childbearing age should ask about reliable forms of birth control while using this medication and for at least 1 week after the last dose. If you become pregnant, talk to your doctor right away about the risks and benefits of this medication. 

• It is unknown if this medication passes into breast milk. Because of the possible risk to the infant, breast-feeding while using this drug and for at least 1 week after the last dose is not recommended. Consult your doctor before breast-feeding.