Lucknow Speciality Pharma
Sacituzumab govitecan-hziy injection was approved for medical use in the United States in 2020. It is on the World Health Organization’s List of Essential Medicines. It is available as a generic medication.
Sacituzumab Govitecan-hziy Injection
- Generic Brand Available – Trodelvy
- API – Sacituzumab Govitecan-hziy
- Packaging – Glass Bottle
- Strength – 180 mg
What is Sacituzumab Govitecan-hziy used for?
- Sacituzumab govitecan-hziy injection is used to treat triple-negative breast cancer that has spread (metastatic) or cannot be removed by surgery (unresectable locally advanced). It is given to patients who have received 2 or more cancer treatments, including at least 1 treatment for metastatic disease.
Facts of Medicines
STORAGE AND HANDLING
Care Sacituzumab Govitecan-hziy Injection must be refrigerated at 2°C to 8°C (36°F to 46°F). Do not use the Sacituzumab Govitecan-hziy Injection beyond the expiration date located on the carton and the vial..
DOSAGE
- Do NOT substitute TRODELVY for or use with other drugs containing irinotecan or its active metabolite SN-38. For intravenous infusion only. Do not administer as an intravenous push or bolus.
- The recommended dose is 10 mg/kg once weekly on Days 1 and 8 of continuous 21-day treatment cycles until disease progression or unacceptable toxicity.
- Premedication for prevention of infusion reactions and prevention of chemotherapy-induced nausea and vomiting is recommended.
- Monitor patients during the infusion and for at least 30 minutes after completion of infusion. Treatment interruption and/or dose reduction may be needed to manage adverse reactions.
SIDE EFFECTS
- The following clinically significant adverse reactions can occur with Sacituzumab Govitecan-hziy Injection: Cardiovascular Toxicity, Myelosuppression, Hypersensitivity, Hypertension, Pancreatic Toxicity.
WARNINGS AND PRECAUTIONS
- Genetic testing should be indicated in order to detect whether a person is at higher risk of developing hypersensitivity.
- Sacituzumab Govitecan-hziy Injection may not be added as a single agent when antiretroviral regimens are changed because of loss of the virologic response.
- Patients with liver disease should be watchful and cautious in order to Sacituzumab Govitecan-hziy Injection because it can aggravate the condition.
In patients with Sacituzumab Govitecan-hziy Injection, conditions like immune reconstitution inflammatory syndrome, a change in body fat as well as an increased risk of heart attack may occur. - Sacituzumab Govitecan-hziy Injection is not recommended for use in infants who are under 3 months of age.
- Cases like lactic acidosis and severe hepatomegaly with steatosis occurred with the use of nucleoside analogues.
- Sometimes serious hypersensitivity reactions have been associated with Sacituzumab Govitecan-hziy Injection..
FAQs – Medicine Questions
Is sacituzumab govitecan-HZIY chemotherapy?
Sacituzumab govitecan-hziy injection is used to treat triple-negative breast cancer that has spread (metastatic) or cannot be removed by surgery (unresectable locally advanced). It is given to patients who have received 2 or more cancer treatments, including at least 1 treatment for metastatic disease.
What kind of drug is sacituzumab?
Image result for Sacituzumab Govitecan-hziy uses
Sacituzumab Govitecan Approved for Metastatic Triple-Negative Breast Cancer. Sacituzumab govitecan is an antibody–drug conjugate made up of an anti–Trop-2 antibody linked to the chemotherapy drug SN-38.
How is sacituzumab govitecan given?
Where can I buy Sacituzumab Govitecan-hziy Injection?
You can buy Sacituzumab Govitecan-hziy Injection from any authorized whole-seller after getting a prescription from a qualified doctor. It is always better to check the credential of the whole-seller/supplier/exporter before buying the product.
The buyer should check the existing law in their home country before importing the product.
What is the procedure to buy Sacituzumab Govitecan-hziy Injection?
Patients can simply fill the order form or can send mail at info@lucknowpharma.com Patients can also send WhatsApp messages to +91-9555306364 We will reply ASAP with the details of the Sacituzumab Govitecan-hziy Injection price as well as procurement procedure.
Note:- The order will be confirmed only after the receipt of the Valid prescription of the Clinician.
Is Trodelvy an immunotherapy?
NEWS / UPDATES