Lucknow Speciality Pharma

Elexacaftor, Tezacaftor and Ivacaftor tablets 150 mg
Elexacaftor, Tezacaftor and Ivacaftor tablets combination is used to treat cystic fibrosis (CF) in patients who have at least one copy of F508del mutation in their CF transmembrane conductance regulator (CFTR) gene or another mutation that is responsive to this medicine To get access, please contact Patient Support Team @ +91 9760014849 / 9555306364 / 9794360370 / 9140551027, Time 9 am - 8 pm IST or send us a request on email (urgent@lucknowpharma.com) / WhatsApp for the same.
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Elexacaftor, Tezacaftor and Ivacaftor Tablets was approved for medical use in the United States in 2019. It is on the World Health Organization’s List of Essential Medicines. It is available as a generic medication.

Elexacaftor, Tezacaftor and Ivacaftor tablets Available Price In Lucknow Banaras Nepal

Elexacaftor, Tezacaftor and Ivacaftor Tablets

  • Generic Brand Available –Trakafta 
  • API – Elexacaftor, Tezacaftor and Ivacaftor
  • Packaging – 60 Tablets
  • Strength – 150 mg

What is Elexacaftor, Tezacaftor and Ivacaftor used for?

Elexacaftor/tezacaftor/ivacaftor and ivacaftor tablets combination is used to treat cystic fibrosis (CF) in patients who have at least one copy of F508del mutation in their CF transmembrane conductance regulator (CFTR) gene or another mutation that is responsive to this medicine.

 

Facts of Medicines

Elexacaftor, Tezacaftor and Ivacaftor tablets 150 mg

STORAGE AND HANDLING

These tablets should be stored at 20° to 25°C (68° to 77°F); excursions permitted to 15°to 30° C (59° to 86° F) [ Controlled Room Temperature]. Keep away from children.

DOSAGE

  • For oral use. Patients should be instructed to swallow the tablets whole
  • TRIKAFTA® (elexacaftor/tezacaftor/ivacaftor and ivacaftor) should be taken with fat-containing meals or snacks. Examples include food prepared with butter or oils or those containing eggs, cheeses, nuts, whole milk, or meats

SIDE EFFECTS

  • Most common adverse reactions include nausea, abdominal pain, headache, fatigue, vomiting, diarrhea, loss of appetite, and trouble sleeping.
  • More severe side effects of Elexacaftor, Tezacaftor and Ivacaftor include hypersensitivity, dark colored urine, yellowish of the skin, yellowish of the whites of the eyes, irregular heartbeat, stomach pain and unusual muscle pain. Symptoms of hypersensitivity include rash, fever/chills, depression, anxiety, and shortness of breath.

WARNINGS AND PRECAUTIONS

  • Genetic testing should be indicated in order to detect whether a person is at higher risk of developing hypersensitivity.
  • Elexacaftor, Tezacaftor and Ivacaftor may not be added as a single agent when antiretroviral regimens are changed because of loss of the virologic response.
  • Patients with liver disease should be watchful and cautious in order to Elexacaftor, Tezacaftor and Ivacaftor because it can aggravate the condition.
  • In patients with Elexacaftor, Tezacaftor and Ivacaftor, conditions like immune reconstitution inflammatory syndrome, a change in body fat as well as an increased risk of heart attack may occur.
  • Elexacaftor, Tezacaftor and Ivacaftor is not recommended for use in infants who are under 3 months of age.
  • Cases like lactic acidosis and severe hepatomegaly with steatosis occurred with the use of nucleoside analogues.
  • Sometimes serious hypersensitivity reactions have been associated with Elexacaftor, Tezacaftor and Ivacaftor.

    FAQs – Medicine Questions

    Elexacaftor, Tezacaftor and Ivacaftor tablets 150 mg
    What is Elexacaftor, Tezacaftor and Ivacaftor?
    The combination of elexacaftor, tezacaftor, and ivacaftor is used to treat certain types of cystic fibrosis (an inborn disease that causes problems with breathing, digestion, and reproduction) in adults and children 6 years of age and older. It should be used only in people with a certain genetic make-up.
    How to take Elexacaftor, Tezacaftor and Ivacaftor Tablets?
    Ivacaftor functions as a potentiator of the CFTR protein for common gating mutations, allowing for an increase in chloride ion flow. Tezacaftor functions as a corrector to facilitate the folding and presentation of the mature CFTR protein to the cell surface, improving CFTR function for the F508del mutation
    What is the mechanism of ivacaftor?
    While the specific mechanism of action is unknown, ivacaftor is thought to restore the flow of chloride ions through the cell membrane via CFTR, and thereby reduce the symptoms of CF in patients with a gating defect.
    Where can I buy Elexacaftor, Tezacaftor and Ivacaftor Tablets?

    You can buy Elexacaftor, Tezacaftor and Ivacaftor Tablets  from any authorized whole-seller after getting a prescription from a qualified doctor. It is always better to check the credential of the whole-seller/supplier/exporter before buying the product.

    The buyer should check the existing law in their home country before importing the product.

    What is the procedure to buy Elexacaftor, Tezacaftor and Ivacaftor Tablets?

    Patients can simply fill the order form or can send mail at info@lucknowpharma.com Patients can also send WhatsApp messages to +91-9555306364 We will reply ASAP with the details of the Elexacaftor, Tezacaftor and Ivacaftor Tablets price as well as procurement procedure.

    Note:- The order will be confirmed only after the receipt of the Valid prescription of the Clinician.

    Does Trikafta increase life expectancy?
    Use of Trikafta could mean an increase in the life expectancy of cystic fibrosis patients, and for young children who begin the treatment early, “They might never have to experience the symptoms of cystic fibrosis in the same way prior to Trikafta,” Quinn said.

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