Lucknow Speciality Pharma
Daunorubicin and cytarabine Injection, On August 3, 2017, the FDA granted regular approval to Vyxeos (also known as CPX-351; Jazz Pharmaceuticals), a liposomal formulation of daunorubicin and cytarabine in a fixed combination, for the treatment of adults with newly diagnosed therapy-related acute myeloid leukemia (t-AML) or acute myeloid leukemia (AML) .
Daunorubicin and Cytarabine Injection
- API – Daunorubicin and Cytarabine
- Packaging – Glass Bottle
- Strength – 100 mg
- Brand name – Vyxeos
What is Daunorubicin and Cytarabine Injection used for?
Daunorubicin and cytarabine Injection is a prescription medicine used to treat the symptoms of Acute Myeloid Leukemia. Vyxeos may be used alone or with other medications. Vyxeos belongs to a class of drugs called Antineoplastics, Anthracycline; Antineoplastics, Antimetabolite.
It is not known if Vyxeos is safe and effective in children younger than 1 year of age.
Facts of Medicines
HOW SUPPLIED/STORAGE AND HANDLING:
STORE AT 20°C TO 25°C (68°F TO 77°F). AVOID EXCESSIVE HEAT AND DO NOT FREEZE. THE CONTAINER CLOSURE OF MEDICATION IS NOT MADE WITH NATURAL RUBBER LATEX.
DOSAGE
Available as a fixed-combination preparation containing a 1:5 molar ratio of daunorubicin to cytarabine coencapsulated in liposomes (daunorubicin/cytarabine liposomal).
Each single-dose vial contains 44 mg of daunorubicin and 100 mg of cytarabine coencapsulated in liposomes.
Calculate dosage of the fixed combination based on the daunorubicin component.
SIDE EFFECTS
Vyxeos may cause serious side effects including:
- hives,
- difficulty breathing,
- swelling of your face, lips, tongue, or throat,
- easy bruising,
- unusual bleeding (nose, mouth)
- any bleeding that will not stop,
- weakness,
- dizziness,
- severe stomach pain,
- black or bloody stools,
WARNINGS AND PRECAUTIONS
- Before staring daunorubicin and cytarabine (lipsomal) treatment, make sure you tell your doctor about any other medications you are taking (including prescription, over-the-counter, vitamins, herbal remedies, etc.). Do not take aspirin, products containing aspirin unless your doctor specifically permits this.
- People who have had a serious allergic reaction with daunorubicin, cytarabine, or any component of this medication cannot take daunorubicin and cytarabine (liposomal).
- Do not receive any kind of immunication or vaccination without your doctor’s approval while taking daunorubicin and cytarabine (liposomal).
- Inform your health care professional if you are pregnant or may be pregnant prior to starting this treatment. Pregnancy category D (daunorubicin and cytarabine [liposomal] may be hazardous to the fetus. Women who are pregnant or become pregnant must be advised of the potential hazard to the fetus).
- For both men and women: Use contraceptives, and do not conceive a child (get pregnant) while taking daunorubicin and cytarabine (liposomal). Barrier methods of contraception, such as condoms, are recommended for up to 6 months after last dose of daunorubicin and cytarabine (lipsomal).
- Do not breast feed while taking daunorubicin and cytarabine (lipsomal) and for at least 2 weeks after the last dose.
FAQs – Medicine Questions
What is Daunorubicin and Cytarabine Injection?
- To treat adults who have been newly diagnosed with acute myeloid leukemia related to therapy (t-AML).
- To treat adults who have been newly diagnosed with AML with changes related to the bone marrow not functioning properly and not producing enough blood cells (AML with myelodysplasia-related changes).
How is Daunorubicin and Cytarabine Injection supplied?
- Daunorubicin and cytarabine (liposomal) is given as an infusion into the vein (intravenous or IV) over 90 minutes.
- You will be given anti-nausea medications approximately 30 minutes before the infusion to reduce the risk of chemotherapy-induce nausea or vomiting.
How Daunorubicin and Cytarabine Works?
Cancerous tumors are characterized by cell division, which is no longer controlled as it is in normal tissue. “Normal” cells stop dividing when they come into contact with like cells, a mechanism known as contact inhibition. Cancerous cells lose this ability. Cancer cells no longer have the normal checks and balances in place that control and limit cell division. The process of cell division, whether normal or cancerous cells, is through the cell cycle. The cell cycle goes from the resting phase, through active growing phases, and then to mitosis (division).
Where can I buy Daunorubicin and Cytarabine Injection injection?
You can buy Daunorubicin and Cytarabine Injection from any authorized whole-seller after getting a prescription from a qualified doctor. It is always better to check the credential of the whole-seller/supplier/exporter before buying the product.
The buyer should check the existing law in their home country before importing the product.
What is the procedure to buy Daunorubicin and Cytarabine Injection?
Patients can simply fill the order form or can send mail at info@lucknowpharma.com Patients can also send WhatsApp messages to +91-9555306364 We will reply ASAP with the details of the Daunorubicin and Cytarabine Injection price as well as procurement procedure.
Note:- The order will be confirmed only after the receipt of the Valid prescription of the Clinician.
NEWS / UPDATES